It is an easy question if you know the normal distribution curve Trypsinogen is activated to trypsin by enteropeptidase (enterokinase) in small intestine. It is the most suitable answer as you should start conversation with open ended question Stage 2: myocarditis, meningitis and neuropathies. If this process is defective, collagen will be defective leading to easy bruising,poor wound healing,subperiosteal hemorrhage and corkscrew hair. Vitamin c is important in the step of hydroxylation of aminoacids proline and lysine. Patients with scurvy has vitamin c deficiency ,which is very important in collagen synthesis. HOX gene is important in embryo development and vitamin A is very teratogenic due to its effect on developmental genes as HOX gene. Fat soluble vitamins like vitamin A uses intracellular receptor as they penetrate cell membrane without carrier,after that they activate a cascade -or act themselves- that bind DNA increasing or decreasing transcription process (acting as transcription factor).
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